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Apparatus and System for Rapid Diagnosis of Malignant Lesions from Biopsy Tissues for Use Inside the Operation Room.

Inventors: Hardik J Pandya, Anil Vishnu G K, Bhagaban Behera, Saeed Rila, Midhun C Kachappilly, Arun Baby and Annapoorni Rangarajan

Patent Application Number:

International: PCT/IB2021/055611

Indian: TEMP/E1/33093/2020-CHE

   Publications:

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  1. GKA Vishnu, T Sakorikar, A Baby, C Singh, A Rangarajan, HJ PandyaIEEE. Bimodal characterization of breast biopsy tissues using MEMS-based biochips: Toward improved tumor delineation Sensors Journal 21 (21), 2021/9/14

  2. V GK, G Gogoi, B Behera, S Rila, A Rangarajan, HJ Pandya. RapidET: a MEMS-based platform for label-free and rapid demarcation of tumors from normal breast biopsy tissuesAMicrosystems & Nanoengineering 8 (1), 1, 2022/1/17

  3. Anil Vishnu G. K., Tamasa De, Arjun B. S., Annapoorni Rangarajan, and Hardik J. Pandya. Towards the development of a table-top system for tumour delineation using electro-thermal characterization. IEEE CONNECT 2021, 9 July 2021. 

  4. Anil Vishnu GK, Annapoorni Rangarajan, Hardik J. Pandya. A portable MEMS-based platform for the electro-thermal phenotyping of breast biopsy tissue: towards a system for tumour delineation. EECS Research Student Symposium, IISc, May 2021.

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  1. Bhagaban Behera, G.K. Anil Vishnu, Suman Chatterjee, V.S.N. Sitaramgupta V, Niranjana Sreekumar, Apoorva Nagabhushan, Nirmala Rajendran, B.H. Prathik, Hardik J. Pandya. Emerging technologies for antibiotic susceptibility testing, Biosensors and Bioelectronics, Volume 142, 2019, 111552, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2019.111552.

  2. Safavieh M, Pandya HJ, Venkataraman M, Thirumalaraju P, Kanakasabapathy MK, Singh A, Prabhakar D, Chug MK, Shafiee H. Rapid Real-Time Antimicrobial Susceptibility Testing with Electrical Sensing on Plastic Microchips with Printed Electrodes. ACS Appl Mater Interfaces. 2017 Apr 12;9(14):12832-12840. doi: 10.1021/acsami.6b16571. Epub 2017 Mar 30. PMID: 28291334; PMCID: PMC5695042.

  3. Anil Vishnu G K, Bhagaban Behera, Alekya B, Arjun B S, Suman Chatterjee, Arun Baby, Saeed Rila, Misaal Khan, Arpitha R, Prathik B H and Hardik J. Pandya. A Novel Microengineering-based Portable Platform for Rapid Real-time Antibiotic Susceptibility Testing. International Conference on Nanoscience and Materials World, Barcelona, Spain, November 18-19, 2019.

  4. Anil Vishnu G K, Bhagaban Behera, Arjun B S, Arun Baby, Niranjana Sreekumar, Saeed Rila, Prathik B, and Hardik J. Pandya. A point-of-care platform for rapid antibiotic susceptibility testing using electrical sensing. Sensors in Medicine, London, the United Kingdom, September 22-23, 2019.

Apparatus for High-Throughput Rapid Antibiotic Susceptibility Testing and Methods Thereof.
Inventors: Hardik J Pandya, Anil Vishnu G K, Bhagaban Behera, Alekya B, Arun Baby, Saeed Rila B C, Arjun B S, Midhun C Kachappilly, Prathik BH, Dipshikha Chakravortty and Nagasuma Chandra

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Indian Patent Application Number: TEMP/E-1/26941/2020-CHE

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  1. Arif Mohd. Kamal, Uttam M. Pal, Manu K.S., and Hardik J. Pandya. Towards the Development of an Intraoperative Probe for Breast Cancer Margin Assessment. Biophotonics Congress: Biomedical Optics, April 2022 , USA.

  2. Uttam M. Pal, Arif Mohd Kamal, and Hardik J. Pandya. Opto-acoustic multimodal system to delineate adjacent normal from cancerous tissue to aid intraoperative breast cancer excisional surgery. IEEE CONNECT 2021, 9 July 2021.

  3. Uttam M. Pal, Arif Mohd Kamal, Ashika Nayak, Tejaswi Medisetti, and Hardik J. Pandya. Towards an Opto-Thermo-Acoustic (OTA) based Diagnostic Tool to Delineate Adjacent Normal from Cancerous Tissue for Cancer Margin Assessment. European Conferences on Biomedical Optics, 20 June 2021.

A multimodal intraoperative probe for breast cancer margin assessment and methods thereof
Inventors: Hardik J Pandya, Arif Mohd. Kamal, Uttam M. Pal, Arjun B. S., and Manu K. S.

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Indian Patent Application Number: 202241012649 

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   Publications:

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  1. A. BS, A. B, H. RS, V. V, A. Mahadevan and H. J. Pandya. Electromechanical Characterization of Human Brain Tissues: A Potential Biomarker for Tumor Delineation. In IEEE Transactions on Biomedical Engineering, vol. 69, no. 11, pp. 3484-3493, Nov. 2022, doi: 10.1109/TBME.2022.3171287.

  2. A. BS, A. V. Gk, S. Rao, M. Beniwal and H. J. Pandya. Electrical Phenotyping of Human Brain Tissues: An Automated System for Tumor Delineation. In IEEE Access, vol. 10, pp. 17908-17919, 2022, doi: 10.1109/ACCESS.2022.3149803.

  3. Arjun B S, V S N Sitaramgupta V, Aswin S, Shilpa Rao, and Hardik J. Pandya. A System-based Approach for the Evaluation of Electromechanical Properties of Brain Tumors. 44th IEEE EMBC International Engineering in Medicine and Biology Conference, July 11-15, 2022, Glasgow, Scotland. 

An in-vivo, intraoperative probe for brain tumour margin delineation and methods thereof
Inventors: Hardik J Pandya, Arjun B S, Anil Vishnu G. K., Gokul A M, Arun Baby, Shilpa Rao, Vikas V,
Manish Beniwal and Anita Mahadevan.

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Patent Application Number:

International: PCT/IB2021/055027

Indian: 202041022728

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Reusable drug delivery device.
Inventors: Hardik J Pandya, Arjun B S, Ajay Krishnan A, Adithya Kumar, and Paramesh H.

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Indian Patent Application Number: 202241018326 

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   Publications:

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  1. Rathin K. Joshi, Manu K S, Hari R S, Mahesh Jayachandra, Hardik J. Pandya. Design, Development, and Validation of a Portable Visual P300 Event-Related Potential Extraction System. Biomedical Circuits and Systems Conference (BIOCAS 2022), Oct. 13-15, Taipei, Taiwan.

An apparatus for attaching a camera to a microscope.
Inventors: Hardik J Pandya, Aswin S, Hari R S, Akhil M, and Arjun B S.

 

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Indian Design Patent Application Number:

367940-001

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A reusable multiangle intradermal drug delivery device.
Inventors: Hardik J Pandya, Arjun B S, Ajay Krishnan A, and Pushkraj Anil Janwadkar

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Indian Patent Application Number: 202241033770

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   Publications:

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  1. B. Alekya, V. S. N. Sitaramgupta V., A. B. S. and H. J. Pandya. Sensor for Meso-Scale Tissue Stiffness Characterization. IEEE Sensors Journal, vol. 22, no. 7, pp. 6442-6453, 2022, doi: 10.1109/JSEN.2022.3154533.

  2. B Alekya, V S N Sitaramgupta V, B S Arjun, V Bhushan, Kevin Abishek, Sanjay Rao, Yeongjin Kim, and Hardik J Pandya. An intubation catheter integrated with flow sensors and smart actuators for characterizing airflow patterns in stenosed trachea: an objective guide for CAO management.  Journal of Micromechanics and Microengineering, 31 (5): 055007. 2021. DOI: 10.1088/1361-6439/abf335

  3. Alekya B and Hardik J. Pandya. Sensorized Catheter for Assessing Airway Stenosis. 44th IEEE Engineering in Medicine and Biology Conference, July 11-15, 2022, Glasgow, Scotland. 

  4. Alekya B, V S N Sitaramgupta V and Hardik J. Pandya. Stiffness Characterization of Healthy and Deficient Tracheal Cartilage Segments using Micromachined Piezoresistive Force Sensor. IEEE Transactions on Biomedical Circuits and Systems, October 06-09, 2021, Berlin, Germany.

  5. Alekya B and Hardik J. Pandya. Design and Development of a Dual-Functional Intubation Catheter for Chronic Airway Management. EECS Research Student Symposium, IISc, May 2021.

  6. Alekya B, Bhushan V, Kevin Abishek, Sanjay Rao, and Hardik J. Pandya. A Steerable Intubation Catheter Integrated With MEMS-based Sensors for Chronic Airway Management. Biomedical Engineering and Instrumentation Summit, Boston, Massachusetts, April 2021.

  7. Alekya B., Sanjay Rao, Hardik J. Pandya. A Steerable Intubation Catheter Integrated with Microelectromechanical System based Sensors for Chronic Upper Airway Management. 13th International Conference on BioMEMS and Medical Microsystems, Amsterdam, The Netherlands, December 2-3, 2019.

A diagnostic tool for grading stenosis in  upper airway and Methods for Characterizing the Same​ 
Inventors: Hardik J Pandya, Alekya B, Bhushan V, V S N Sitaram Gupta V, Arjun B S, Kevin Abhishek, S Siddesh Shenoy, Sanjay Rao and Mayur Bhuva

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Patent Application Number:

International: PCT/IB2021/054690

Indian: TEMP/E-1/30202/2020-CHE

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   Publications:

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  1. Alekya B, Hardik J. Pandya. Sensorized Catheter for Quantitative Assessment of the Airway Caliber. 13th EECS Research Students Symposium, IISc, April 2022.

Device to measure airway patency.
Inventors: Alekya B, Aswin S, Akhil M, S Siddesh Shenoy, Sanjay Rao and Hardik J. Pandya 

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Indian Design Patent Application Number:

364765-001

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